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Turkish Journal of Cancer
1997, Volume 27, Number 3, Page(s) 98-103
[ Summary ]
Treatment of advanced prostatic cancer with orchiectomy and cyproterone acetate
ATİLA TATLIŞEN, GÜRKAN ÖRSKIRAN, MUSTAFA KARACAGİL, UĞUR YILMAZ
Department of Urology, Erciyes University Medical School, Kayseri-Turkey

Twenty-eight previously untreated cases of prostate adenocarcinoma with stage C and D disease have been treated with orchiectomy and cyproterone acetate between 1990-1994. The patients were evaluated with intravenous urography, bone X-rays, serum levels of prostatic acid phosphatase and prostate specific antigen, bone scintigraphy and digital rectal examination performed before and after the treatment. The patients were followed within a range of 9-26 months. Fifteen cases showed partial response, 7 cases had stable disease and 6 cases had progressive disease. Four of the progressive cases died in the follow-up period. Bilateral orchiectomy combined with cyproterone acetate may be suitable treatment modality with few side effects in the management of advanced prostate cancer.

[ Summary ]
Turkish Journal of Cancer web sitesi Novartis Onkoloji'nin karşılıksız eğitim katkılarıyla hazırlanmıştır.
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