[ Main Page | Editorial Board | About | Instructions ]
[ Table of Contents | Archive | Archive Search | Online Submission | Sponsor | E-mail ]

Turkish Journal of Cancer
2007, Volume 37, Number 3, Page(s) 098-108
[ Summary ] [ Full Text ] [ PDF ]
Clinical characteristics and therapy outcome of pediatric Hodgkin’s lymphoma - a single centre experience from the west part of Turkey
KAMER MUTAFOĞLU UYSAL1, RIZA ÇETİNGÖZ2, DİLEK GÜNEŞ1, AYŞE DEMİRAL2, ERDENER ÖZER3, HANDAN ÇAKMAKÇI4, EMRE ÇEÇEN1, FAİK SARIALİOĞLU1, NUR OLGUN1
1Dokuz Eylül University Institute of Oncology, Department of Pediatric Oncology, İzmir-Turkey
2Dokuz Eylül University Faculty of Medicine, Departments of Radiation Oncology, İzmir-Turkey
3Dokuz Eylül University Faculty of Medicine, Departments of Pathology, İzmir-Turkey
4Dokuz Eylül University Faculty of Medicine, Departments of Radiodiagnostics, İzmir-Turkey

The aim of this study was to evaluate the epidemiologic and clinicopathological characteristics and treatment outcome of pediatric Hodgkin’s lymphoma (HL) cases treated in our institution. The patient records were reviewed retrospectively. Thirty-eight patients were eligible out of 51. The median age was 10 years and M:F ratio was 1.7:1. The major histological subtype was nodular sclerosis. The treatment regimen was COPP and/or ABVD + involved- field radiotherapy (IFRT) in 24, and GPOH-HD 90 + IFRT in 13 patients. Median follow-up was 105 months. At 5 and 10 years event-free survival rates were 77% and 73%; overall survival rates were 96% and 92%, respectively. Survival rates were comparable with the other studies from Turkey. No prognostic factor could be determined owing to the limited patient number. The epidemiologic and clinical features of pediatric HL may show considerable differences even between the regions of a country. We need large scale national trials to determine our own risk factors and design risk-based therapy regimens accordingly [Turk J Cancer 2007;37(3):98-108]

[ Summary ] [ Full Text ] [ PDF ]
Turkish Journal of Cancer web sitesi Novartis Onkoloji'nin karşılıksız eğitim katkılarıyla hazırlanmıştır.
[ Main Page | Editorial Board | About | Instructions ]
[ Table of Contents | Archive | Archive Search | Online Submission | E-mail ]