[ Main Page | Editorial Board | About | Instructions ]
[ Table of Contents | Archive | Archive Search | Online Submission | E-mail ]

Turkish Journal of Cancer
2005, Volume 35, Number 2, Page(s) 070-080
[ Summary ] [ Full Text ] [ PDF ]
Head and neck squamous cell carcinoma: Mansoura 10 years experience
AMAL A.F. HALIM1, SALEH MANSOUR1, HANAN WAHBA1, MOHAMED HEGAZY2, HANY ELDEEB3
1Mansoura University, Faculty of Medicine, Departments of Clinical Oncology and Nuclear Medicine,Mansoura-Egypt
2Mansoura University, Faculty of Medicine, Departments of Surgical Oncology,Mansoura-Egypt
3Northamptonshire Center for Oncology, Northampton-UK

Head and neck (H&N) cancers are the sixth most prevalent cancers in the world with squamous cell carcinoma (SCC) constituting around 90% of it. One hundred and eighty eight patients with H&N SCC were treated at Mansoura University Hospital in the period from January 1990 to December 1999 inclusive. For those 188 cases we analyzed their clinicoepidemiologic data, survival, prognostic factors, patterns of failure and toxicity of therapy. Unfortunately 75.5% of the cases presented in advanced stages. The median eventfree survival duration was 14 months, while the median overall survival duration was 22 months. The 5-year eventfree survival and overall survival were 45% and 53%, respectively. On multivariate analysis for event-free survival, only performance status and grade were significant (p ≤0.05). On the other hand multivariate analysis for overall survival found only performance status and stage to be significant (p ≤0.05). Local failure exceeded in incidence both nodal and distant failure. The majority of our H&N SCC cases presented with advanced stages of the disease. Controlling risk factors and early cancer detection are needed to decrease the incidence and increase the survival of such tumors.[Turk J Cancer 2005;35(2):70-80].

[ Summary ] [ Full Text ] [ PDF ]
[ Main Page | Editorial Board | About | Instructions ]
[ Table of Contents | Archive | Archive Search | Online Submission | E-mail ]