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Turkish Journal of Cancer
1992, Volume 22, Number 3, Page(s) 91-97
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Relations between estrogen receptor status, clinical and histological findings and their prognostic significance in breast carcinoma
M. TEKİN AKPOLAT, EŞMEN BALTALI , ARZU SUNGUR, İLKSER GULYANAR, ŞEVKET RUACAN, DİNÇER FIRAT, GÜLTEN TEKUZMAN, AYŞE KARS
Keywords: Breast cancer, estrogen receptor, histopathologic, prognosis
Summary
Estrogen receptor (ER) status was evaluated in 280 breast cancer patients by the fluorescein labelled estrone method. The ER status was (+) in 130 and (-) in 150 patients. Comparisons have been made between receptor content and: 1) anatomical, clinical and histopathologic features , 2) disease free interval and survival. The following conclusions can be drawn: a) ER positivity is higher in postmenopausal and older patients and in well differentiated tumors, b) There is no significant relationship between ER status and tumor size, tumor stage, elastosis content and axillary node involvement, c) Disease free survival and overall survival is longer in ER (+) patients, this is significant in postmenopausal patients.
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