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Turkish Journal of Cancer
1992, Volume 22, Number 3, Page(s) 121-125
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Treatment and survival of patients with vaginal recurrence of endometrial adenocarcinoma
YAVUZ SALİHOĞLU, HOWARD W. JONES, LONNIE S. BURNETT
Keywords: Endometrial cancer, tumor recurrence
Summary
Two hundred and sixty-five patients with endometrial cancer were seen at the Vanderbilt Uoiversity Medical Center between 1975 and 1989. During this interval, 16 patients with vaginal recurrence were examined. Six of these sixteen patients had been initially treated elsewhere, and after diagnosis of their vaginal recurrence, they were referred to our clinic. Thirteen patients (81%) had no symptoms at the time of diagnosis of the recurrence. Tumor size was less than 2 cm in 13 patients while the remaining 3 patients had tumors between 2 and 4 cm in diameter. The median time interval between primary treatment and detection of recurrence was nine months. Sixtynine percent of all recurrences were detected within one year. Three patients developed “late recurrences” at four, five and eleven years following their original diagnosis. Surgery alone or in combination with radiotherapy was given to 10 of the 16 patients. Two patients received chemotherapy after surgery for their recurrent tumor, and only two women were treated by radiation for vaginal recurrence. The calculated 5-year survival rate for patients with vaginal recurrences was 75%.
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