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Turkish Journal of Cancer
1993, Volume 23, Number 3, Page(s) 134-142
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Bilateral breast cancer treatment results and analysis of prognostic factors
KAYIHAN ENGİN, MUSTAFA ÜNSAL
Department of Oncology and Nuclear Medicine, Okmeydanı Hospital, İstanbul-Turkey
Keywords: Bilateral breast cancer, prognostic factors
Summary
Twenty-nine bilateral breast carcinoma cases among 1,206 patients with carcinoma of breast were analyzed retrospectively. The frequency of bilateral carcinoma of breast among all breast cancer patients was approximately 2.4%. Median age was 46 years at the time of first cancer diagnosis (range, 26-69 years). The majority of the lesions were invasive ductal carcinoma (86%). Of 58 tumors, 30 (52%) were Stage II, 10 (17%) were Stage I, 10 (17%) were Stage IV and 8 (14%) were Stage Ill. Patients were treated with various combinations of surgery, radiation and chemotherapy. Of 29 patients with bilateral breast cancer, 17% presented with simultaneous bilateral disease, 24% with sychronous tumors, whereas 59% developed asynchronous tumors. Age, menopausal status and tumor size at the time of initial cancer correlated with the time interval between two cancers. Interval between two cancers was significantly longer in patients >50 years old (p=0.02). Age, tumor size and nodal status at the time of initial cancer and the time interval between two cancers correlated with overall survival. Tı lesions did significantly better than the rest of the patients (p=0.03).
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